It’s a Molecule, it’s a Chemist, it’s Super Enzyme!

Photo credit whatsthesmatter@blogspot.com

Enzymes 101: The Introduction    

       

It’s amazing how many things our bodies can accomplish without us ever realizing that it’s happening. This is especially amazing when we consider that many of these tasks are absolutely vital to keeping us alive and conscious enough to appreciate it. How many times a day do you notice that you’re blinking? How often do you register your heart beating? For many, the answer is probably rarely (although probably now that you’re thinking about it). There are thousand of actions going on in your body, however, that you will never notice directly, no matter how hard you concentrate on them. These are the chemical reactions that make the difference between semi-organized piles of organic mush, and the living, breathing, navel-gazing individuals we all are. So if you’re happy and you know it, thank your chemistry; without it I can guarantee neither condition would be true.

Some of the chemistry that occurs in our bodies is as simple and spontaneous as the old vinegar and baking soda volcano trick. Any reaction that explodes into reality in a fourth-grade classroom is hardly an energetic challenge. Other reactions, however, are a lot tougher to coax along. Even when some important reactions do occur spontaneously (that is, without other factors interfering in the process) the speed of these chemical reactions, or reaction rate, might be so slow that it wouldn’t be likely to happen over the course of one’s lifetime, much less the multiple times a second required for it to be biologically useful. With all of this difficult chemistry so necessary to stay alive, how do we accomplish these constant chemical feats? Enter the enzyme.

Before discussing the amazing power of enzymes as tools or, as I like to think of them, master chemists, we need to go over a few defining concepts. Enzymes are catalysts. What this means is that although they help to chemically transform something into something else, they emerge from that reaction just the same as when they went in. This is like a baker: without him there is a very VERY small chance that all of the ingredients would jump into the oven together and become a cake, but while they come out transformed into a different and delicious form, he stays the same and is ready to bake another cake. What this means for your body is that unlike sugars, oxygen, and numberless other chemicals that your body has to constantly take in to supply the “ingredients” for your life-chemistry, a single enzyme can contribute over and over to the same chemical reaction without having to be replaced.

Now we have a bit of an idea of what an enzyme’s role in a chemical reaction is, but what is the enzyme itself? Enzymes are macromolecules made up of protein or nucleic acid (or both). A macromolecule is basically what it sounds like: a big molecule. Proteins and nucleic acids are big molecules made up of chains of smaller units. These chains then fold up into a shape that gives the enzyme its function. We’ll talk more about the specific forms and families of enzymes in future articles.

The more you learn about nature, the more you learn what a spectacular problem solving force evolution can be. When it comes to chemistry, the problem-solving power of enzymes is more astounding than the most outrageous magic any fiction writer could ever come up with. So stayed tuned for future posts when I’ll explore the magic mechanisms, resplendent reactions, and elegant evolution of nature’s best chemists!